In 1941 Archbishop John Cantwell asked the Society of St. Columban, also known as the Columban Fathers to administer to the spiritual needs of the growing Filipino population in Los Angeles. Finally in 1945, the first Filipino parish in the Archdiocese of Los Angeles was established concurent the leased of a building at 1035 S. Fedora St., where Sunday Masses were celebrated in 1945-46. (This building is now a Korean kindergarten in Koreatown).
Due to a growing congregation, Father Francis Hoza and the Filipino Community purchased an old 1982 fireshouse at 125 Loma Drive and transformed it into a serviceable church, where the first Mass was celebrated on January 1, 1947. Soon a larger church was needed and the present church was built on the existing site and the first Mass was celebrated on September 10, 1967. On June 30, 1968, the new church was dedicated by His Eminence, James Cardinal McIntyre.
A notable feature of St. Columban Church is its fine mosaics:
The church sits on one of the five hills that circled the old Los Angeles; this hill is called Crown Hill. In the 1890s Crown Hill was the epicenter of a massive oil boom when Edward L. Doheny and Charles A. Canfield bought a lot at Colton Street and Glendale Boulevard; on November 1892 they struck oil and the boom was on. Belmont High School, opposite the church, opened in 1923 on the site of the old Belmont Hotel from which the school got its name; at one time it was the largest public school in America.
The area where the church is situated is part of Historic Filipinotown established on August 2, 2002 in a resolution proposed by then city council member, now Mayor, Eric Garcetti.